KEGG   Mycobacterium tuberculosis H37Rv: Rv2682c
Entry
Rv2682c           CDS       T00015                                 
Symbol
dxs1
Name
(RefSeq) 1-deoxy-D-xylulose 5-phosphate synthase
  KO
K01662  1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]
Organism
mtu  Mycobacterium tuberculosis H37Rv
Pathway
mtu00730  Thiamine metabolism
mtu00900  Terpenoid backbone biosynthesis
mtu01100  Metabolic pathways
mtu01110  Biosynthesis of secondary metabolites
Module
mtu_M00096  C5 isoprenoid biosynthesis, non-mevalonate pathway
Brite
KEGG Orthology (KO) [BR:mtu00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00730 Thiamine metabolism
    Rv2682c (dxs1)
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    Rv2682c (dxs1)
Enzymes [BR:mtu01000]
 2. Transferases
  2.2  Transferring aldehyde or ketonic groups
   2.2.1  Transketolases and transaldolases
    2.2.1.7  1-deoxy-D-xylulose-5-phosphate synthase
     Rv2682c (dxs1)
SSDB
Motif
Pfam: DXP_synthase_N Transket_pyr Transketolase_C TPP_enzyme_C E1_dh PFOR_II Usp
Other DBs
NCBI-GeneID: 887461
NCBI-ProteinID: YP_177898
TubercuList: Rv2682c
UniProt: P9WNS3
Structure
Position
complement(2998052..2999968)
AA seq 638 aa
MLQQIRGPADLQHLSQAQLRELAAEIREFLIHKVAATGGHLGPNLGVVELTLALHRVFDS
PHDPIIFDTGHQAYVHKMLTGRSQDFATLRKKGGLSGYPSRAESEHDWVESSHASAALSY
ADGLAKAFELTGHRNRHVVAVVGDGALTGGMCWEALNNIAASRRPVIIVVNDNGRSYAPT
IGGVADHLATLRLQPAYEQALETGRDLVRAVPLVGGLWFRFLHSVKAGIKDSLSPQLLFT
DLGLKYVGPVDGHDERAVEVALRSARRFGAPVIVHVVTRKGMGYPPAEADQAEQMHSTVP
IDPATGQATKVAGPGWTATFSDALIGYAQKRRDIVAITAAMPGPTGLTAFGQRFPDRLFD
VGIAEQHAMTSAAGLAMGGLHPVVAIYSTFLNRAFDQIMMDVALHKLPVTMVLDRAGITG
SDGASHNGMWDLSMLGIVPGIRVAAPRDATRLREELGEALDVDDGPTALRFPKGDVGEDI
SALERRGGVDVLAAPADGLNHDVLLVAIGAFAPMALAVAKRLHNQGIGVTVIDPRWVLPV
SDGVRELAVQHKLLVTLEDNGVNGGAGSAVSAALRRAEIDVPCRDVGLPQEFYEHASRSE
VLADLGLTDQDVARRITGWVAALGTGVCASDAIPEHLD
NT seq 1917 nt   +upstreamnt  +downstreamnt
atgctgcaacagatccgcgggcccgctgatctgcagcacctttcccaggcgcagcttcgg
gagctggccgccgagatccgtgagttcctgatccacaaggttgccgccacgggggggcat
ctggggccgaacctgggagtggtggaactcaccttggcgctgcaccgggtattcgactcg
ccgcacgatccgatcatcttcgacaccggtcaccaggcctacgtccacaagatgttgacc
ggacgcagccaggacttcgcaaccctgcgtaagaagggcgggttgtcggggtatccgtct
cgtgccgagagcgagcacgactgggtggagtcgagccacgccagcgcggcgctgtcgtac
gcggacgggttggccaaggcgttcgagttgaccggacaccgcaaccggcatgtggtcgcg
gtggtcggtgacggtgcgctcaccggcggtatgtgctgggaggcgctgaacaatatcgcc
gcatcccgccggccggtgattatcgtggtcaacgacaatgggcgcagctacgcgcccaca
atcgggggcgtcgccgaccatctggccacgctgcggctgcagccggcctacgagcaggcg
ctggagacgggccgcgacctggtgcgcgcggtgccgcttgtcggcggtctgtggtttcga
ttcctgcacagcgtcaaggccggcatcaaggactcgctgtcgccgcagttgctgttcacc
gacctcgggttgaagtacgtcggcccggtcgacggccatgacgagcgggcggtggaggtc
gcgctgcgcagcgcgcggcgcttcggtgcaccggtgatcgtgcacgtcgtcacccgcaag
ggcatgggctacccgccggccgaggccgaccaggccgagcagatgcattccacggtcccg
atcgatccggccaccggacaagccaccaaggtggccggcccaggctggacggcgaccttc
tctgatgcacttatcggctacgcccagaaacgccgtgacatcgtggccattaccgcggcc
atgccgggccccaccgggctgaccgcgttcgggcagcgcttcccggatcgattgttcgac
gtcgggatcgccgagcaacacgcgatgacgtcggcggccgggttggcgatgggtgggctg
caccccgtggtggcgatctactcgacgttcctgaaccgggcgttcgaccagatcatgatg
gatgtggcgctgcacaagctgccggtcaccatggtgctggaccgtgccgggatcaccggt
agcgacggcgccagccacaacggaatgtgggacttgtcgatgctgggtatcgtgcccggc
atccgggtggcagcgcccagagacgccacccggttgcgtgaagaactcggcgaggcgctc
gacgtcgacgacggcccgacggcgttacggttccccaaaggtgatgtgggagaagatatt
tcggctttggagcggcgtggaggcgtggatgtgctggcggcgcccgccgatggtttgaac
cacgacgtcctgttggtggccatcggcgcgttcgcaccgatggcgttggcggtggccaag
cggctgcacaaccaggggatcggtgtgacggtgatcgacccgcgctgggtgttgccggtg
tctgacggtgtgcgcgaactggcggtgcagcacaagctgctcgtcacgctagaggacaac
ggggtcaacggtggggcggggtcagcggtgtcggccgcgctgcggcgcgcggagatcgac
gtgccctgccgcgatgtcgggttgccgcaggagttctacgagcacgcgtctcgaagcgag
gtgctggccgatctggggcttaccgaccaggacgtggcccggcggatcaccggctgggtc
gccgcgctgggtaccggggtgtgtgcgtccgacgcgattccagaacatctcgactaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   TUBERCULIST (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
3D Structure (2)   
   PDB (2)   
Protein domain (7)   
   Pfam (7)   
All databases (45)   

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